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RSL-Plus Raman Handheld System
Low-resolution Raman Spectroscopy
When a sample is irradiated with a laser or light of a single frequency, the scattered portion of the light consists primarily of elastically scattered photons, or the Rayleigh component. Some inelastically scattered photons also appear, and comprise the Raman component. The shift in frequency corresponds to the molecular vibrational frequencies of the sample. The Raman spectrum that results provides information about the vibrational structure of the sample (the fingerprint region). Fully Integrated, Compact SystemThe RSL-Plus consists of all the components needed for on-site Raman analysis, including an embedded computer with LCD display that’s preloaded with spectral matching software for convenient QC, verification and validation routines. The rest of the system includes a linear CCD-array spectrometer; a 785 nm diode laser to irradiate the sample; a fiber optic sampling probe for liquids, solids, powders, gels and tablets; and a 2-hour rechargeable battery. In addition, optical fiber makes possible remote sampling at distances of up to 200 meters. The RSL-Plus is self-calibrating and has automated validation features. Its operating software is compliant with the FDA’s 21-CFR-11, and includes features such as audit logging, spectral matching, database creation, and automatic detection of data tampering. Specifications
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Article on Low-resolution Raman Spectroscopy
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